For ingestion within 2 hours: activated charcoal.Withhold further doses of anticoagulant.Send coagulation profile, including relevant levels (dabigatran level, aPTT, TT, prothrombin time and/or anti-Xa level).Organise urgent FBC, group and hold, creatinine.(2014) New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural / bleeding management, Internal Medicine Journal, vol. NOAC Guidelines: Management of NOAC associated bleeding (CEC, July 2017).Most concerns regarding NOACs in the ED relate to reversal or commencement. NOACs currently registered for use in Australia include: dabigatran (Pradaxa), rivaroxaban (Xarelto) and apixaban (Eliquis).
Previously, warfarin was the only oral anticoagulant available in Australia however since the introduction of NOACs, this has increased the drug choices available for oral anticoagulation.
Also known as “Non-Vitamin-K-antagonist Oral Anticoagulants” (NOACs) or “Direct Oral Anticoagulants” (DOACs).
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